COMPASSION. EXPERIENCE. RESPECT.

We Clean Tough Situations: Colorado Suicide, Crime Scene, Hoarding, and Biohazard Cleanup

Bio-One of Colorado helps families and communities after life’s most challenging moments. We clean what others can’t—biohazards, trauma, crime, and suicide scenes, hoarding, and more.

Our trained team shows up fast, works with care, and treats your space with respect.

  • Available 24/7.
  • Discreet arrival—unmarked vehicles upon request.
  • We work with insurance.
  • Locally owned and trusted.

Real help for real life: let us handle the cleanup, so you can focus on the path ahead.

Emergency response hotline

Get in touch with our 24/7 biohazard & crime scene cleaning team today

Call me directly:Matt and Krista Gregg
Call
Respond
Clean

Venkat Mylavarapu

The service was very good. Matt was very professional and did great job. He took time to make sure that every corner was cleaned and also at very reasonable price.

Michelle Koeniger

We needed sewage mitigation done in our basement. Our technician Sam did an amazing job! He was very prompt and responsive to our questions. It so nice to have peace of mind knowing tha...

Carolyn Tiffany

They did a Wonderful job and were Very, Professional and Attentive!!! Thank you, So Much!

Joslyn Owens

Bio-One have a very friendly service. They look out for your best interest when doing the job. They did an great job cleaning and sanitizing my crawl space.

Kayla Zechmann

"My sister's family used Bio-One of Colorado for a trauma cleanup and they were very happy with the results. There was no trace of odor or any other material. They were very professio...

Trusted By
National Law Enforcement Memorial Museum Certified
Colorado Department of Public Health & Environment Certified
IICRC Certified
Mental Health First Aid Certified
Decon-Tech Certified
Fentanyl Remediation

Where Crisis Meets Compassion

Bio-One responds when families need more than just cleanup—they need someone who truly cares.
Five Star Experience
CLOSE X

Help first. Business second.

We provide compassionate, discreet biohazard cleanup, restoring safety and peace of mind in times of crisis.
Suicide Cleanup Icon

Suicide Cleanup

We clean with care, helping families begin to heal.

Learn more
Crime Scene Cleanup Icon

Crime Scene Cleanup

We remove hazards so you can move forward safely.

Learn more
Blood Spill Cleanup Icon

Blood Spill Cleanup

We clean thoroughly to restore safety and peace of mind.

Learn more
Hoarding Cleanup Icon

Hoarding Cleanup

We are here to earn your trust and ease you into the hoarding cleanup process.

Learn more
Decomposition / Undiscovered Death Icon

Decomposition / Undiscovered Death

We handle the toughest scenes with dignity and compassion.

Learn more
Medical Waste Disposal Icon

Medical Waste Disposal

We offer medical waste disposal and train others on its safe handling.

Learn more
Emergency Vehicle Decontamination Icon

Emergency Vehicle Decontamination

We help protect first responders with deep, professional cleaning.

Learn more
Odor Removal Icon

Odor Removal

We will find the source and remediate it.

Learn more
View All Services

We respond 24/7.
Request a service now.

Bio-One of Colorado

    By checking this box, you consent to receive up to 5 SMS messages per week from Bio-One at the phone number provided related to conversational purposes. Message frequency may vary. Standard message and data rates may apply. You may reply STOP to opt-out at any time. For assistance, respond HELP or visit Contact us. View our Privacy Policy or Terms and Conditions for more information.
    SMS is extremely convenient for our representatives and used exclusively for the purpose of delivering our services. We do not sell or deliver SMS data to third parties for marketing purposes. For more information please visit Privacy Policy

    WE'RE READY 24/7

    Work with us

    Three simple steps. One compassionate team.
    1

    Call Anytime—Day or Night

    Reach out 24/7. A kind, trained expert will listen and guide you through the next steps.
    2

    On-Site, With Care

    We’ll arrive quickly, walk the space with you, and create a plan that fits your needs—with total discretion and respect.
    3

    You're in Good Hands

    We’ll handle the cleanup with care and follow through until you’re fully satisfied. We can even work with your insurance to ease the process.

    Ready For Anything 24/7/36

    Three simple steps. One compassionate team.
    Always here. Always ready. No matter the hour, you’ll reach someone who listens, cares, and knows how to help.

    Call us anytime—24/7/365—for fast, compassionate service from a local Bio-One expert.
    Schedule a Service
    Why choose Bio-One of Colorado?

    Trusted When It Matters Most

    Because you deserve more than just a cleanup—you deserve care.

    Families, property owners, and first responders choose Bio-One for fast, discreet, and compassionate cleanup.

    People call us during some of their most challenging moments. We show up fast, listen first, and handle every scene skillfully and compassionately.

    • Fast, local 24/7 response
    • Trained experts who treat you with respect
    • Discreet, thorough cleanup from start to finish
    • We handle the insurance, so you don’t have to

    We’re here to help you feel safe again—and we’ll walk with you every step of the way.

    Call Us 27/4
    Your Local Cleanup Partner

    Rooted in the community. Driven by compassion.

    The person behind your local Bio-One isn’t just a business owner—they’re a neighbor who cares deeply about helping others through life’s most challenging moments. Trained, certified, and ready to respond 24/7, they lead a team committed to doing the right thing with discretion, empathy, and professionalism.

    You can trust that when you call, you get real help from someone who truly understands.

    Matt and Krista Gregg

    Matt and Krista Gregg are the dedicated faces behind Bio-One of Colorado, embodying the core values of compassion, professionalism, and respect. Krista, a Colorado native, brings a deep understanding of the Denver Metro area community and culture. She is a Colorado State University grad and has 10+ years of experience in marketing and communications, most recently serving at the Director of Marketing for the Bio-One Inc corporate office. Before joining Bio-One, Matt worked for both DirecTV and DISH Network, and most recently he was the General Manager at a successful Ford dealership where he was recognized as one of Automotive News' Top 40 under 40 in 2018. Together, they channel their experiences into Bio-One's mission, offering empathetic, expert services in challenging situations, ensuring everyone they help receives care that's not just professional, but deeply understanding and respectful.
    Learn more about me and my mission
    Call Us 24/7

    Real People. Real Compassion.

    Our local team is trained, experienced, and here to help—no judgment, just support.

    We understand that calling us means something serious has happened. That’s why our local Bio-One team brings more than training—we bring compassion, clear communication, and respect every step of the way.

    • Highly trained and experienced technicians
    • Honest, in-person estimates
    • Discreet and professional service
    • Locally owned and operated

    You can count on us to handle it all—with care.

    Meet my team

    What our clients say

    decontamination and biohazard cleaning services reviews
    Kayla Zechmann, Thornton, 10/2023
    "My sister's family used Bio-One of Colorado for a trauma cleanup and they were very happy with the results. There was no trace of odor or any other material. They were very professional and easy to work with during the process. I was helping my sister do legwork for this difficult situation from out of state, and speaking with Matt made me feel a lot more comfortable about choosing someone for this important service based on Google reviews."
    decontamination and biohazard cleaning services reviews
    Aubrey Boggs, Thornton, 8/2023
    So while I did not pay for services from Bio One I did receive incredibly helpful advice from the owner Matt when I called today! I had a small mold situation I was concerned about and unsure how to effectively get rid of it. Despite the fact that I easily would’ve paid whatever the company’s fee was, Matt offered me advice that allowed me to fix the problem myself. It was incredibly kind and speaks to the person he is and the business he runs. If I ever do have a situation that requires these kind of services (although I hope I don’t) I will absolutely go to Bio One. Thanks again for your help, Matt!
    decontamination and biohazard cleaning services reviews
    Aubrey Boggs, Elbert County, 07/2023
    So while I did not pay for services from Bio One I did receive incredibly helpful advice from the owner Matt when I called today! I had a small mold situation I was concerned about and unsure how to effectively get rid of it. Despite the fact that I easily would’ve paid whatever the company’s fee was, Matt offered me advice that allowed me to fix the problem myself. It was incredibly kind and speaks to the person he is and the business he runs. If I ever do have a situation that requires these kind of services (although I hope I don’t) I will absolutely go to Bio One. Thanks again for your help, Matt!
    Load More Reviews Leave a Review
    COMMUNITY

    Rooted in the Community, Ready to Help

    We live here, we care, and we’re proud to serve our neighbors.

    We love the people, places, and spirit of the communities we serve. That’s why we show up 24/7—to help our neighbors through tough moments with care, compassion, and respect.

    From local families to first responders, we’re honored to be a trusted part of the community.
    Serving Colorado and Surrounding Areas
    Find your nearest Bio-One office

    Loading map...

    Frequently asked questions

    What types of situations does Bio-One handle?
    We clean biohazards, trauma scenes, suicides, unattended deaths, hoarding situations, and more—discreetly and with care.
    Are you really available 24/7?
    Yes. No matter the time or day, someone from our local team is always ready to answer your call.
    Will my information be kept private?
    Absolutely. Upon request, we arrive in unmarked vehicles and treat every situation with total discretion and respect.
    How quickly can you arrive?
    We respond quickly—usually the same day. We’re locally owned, so we can get to you quickly.
    Do you work with insurance?
    Yes. We’ll work directly with your insurance provider to help make the process easier for you.
    What happens when I call Bio-One?
    A kind, trained expert will listen, explain the next steps, and guide you through the process—no pressure, no judgment.
    Is your team trained for hazardous cleanup?
    Yes. Our technicians are fully trained, certified, and experienced in handling dangerous and sensitive situations.
    Do I have to be home during the cleanup?
    Not if you don’t want to be. We’ll work with your schedule and comfort level every step of the way.
    How long does cleanup usually take?
    It depends on the situation, but most cleanups take a day or two. We’ll give you a clear timeline upfront.
    Why should I trust Bio-One?
    Because we genuinely care. We’re part of your community and show up with compassion, professionalism, and respect—every time.
    24/7 EMERGENCY HOTLINE
    Schedule a Service

    Get in touch with our 24/7 biohazard & crime scene cleaning team today

    Bio-One of Colorado

    Denver Decontamination and Biohazard Cleaning Services

    303 S Broadway Ste 200-482, Denver, CO 80209
    Visit Corporate Office
    ©️2022-2026