ABOUT BIO-ONE

Help First. Business Second.

Bio-One cleans the unimaginable with heart, skill, and respect.

From trauma scenes to hoarding situations, Bio-One is trusted to handle life’s toughest cleanups with compassion and care.

Crime scenes
Hoarding and clutter
Biohazards and trauma
Unattended deaths

For over 20 years, we’ve helped families, businesses, and communities recover and move forward. We're here to help—not to judge.

Call Us 24/7

Trusted By

Welcome to Bio-One

Compassion First. Cleanup Always.

We help people through life’s most challenging moments.

We handle every cleanup with dignity, respect, and care. Whether it's a biohazard, trauma, or hoarding cleanup, our job starts with care—and ends with peace of mind.

20+ years of trusted service
Discreet, respectful, and professional
Available 24/7 across the country
"Help First, Business Second" is how we work

When you need someone you can trust, we’re here.

We Clean Tough Situations.

We always tackle the messiest, hardest cleanups with heart and expert precision. From crime scenes to cluttered homes, we clean what’s tough with care and respect.

Biohazard Cleaning Services

Suicide Cleanup

Crime Scene Cleanup

Blood Spill Cleanup

Decomposition / Undiscovered Death

Medical Waste Disposal

Emergency Vehicle Decontamination

Feces / Urine Cleanup

Homeless Encampment Cleanup

Virus / Bacteria Disinfection

Hoarding Cleaning

Homeless Encampment Cleanup

Deep Cleaning

Recover Valuables

Who We Serve

Helping People, Families, and Communities

No matter who calls, we respond with care, respect, and expert support.

We work with:

Homeowners
Business owners
Law enforcement & first responders
Government and public health agencies

Whether it’s a family in crisis or a public space in need, we show up with care, discretion, and expert cleanup. Every job is different, but our mission stays the same: to help people feel safe, supported, and ready to move forward.

More Than a Cleanup Crew

Why People Trust Bio-One

Real Help. Real Fast. From People Who Care.

During difficult times, we’re here to help—quick, kind, and capable. We handle the cleanup so you can focus on what comes next. Here’s what you can count on from us:

Fast Response

We’re available 24/7 and act quickly.

Trained Experts

Certified, experienced, and ready for anything.

Compassion First

We lead with care, not judgment.

Insurance Help

We work with your provider to make things easier.

Local Support

We partner with the people who care about your community, too.

How We Work

It Starts with One Call

We take it from there—restoring safety, calm, and comfort. When you call Bio-One, here’s what happens:

You Call – We're here 24/7 to answer and respond fast.
We Arrive – Local experts show up quickly and ready to help.
We Assess – We walk through the space, explain what needs to be done, and answer your questions.
We Clean – We carefully clean, disinfect, and remove any biohazards.
We Make it Right — Our goal is to restore your space and peace of mind to normal.

We're by your side from the first call to the final walkthrough.

Here for You, Right Here in Your Community

Locally owned. Personally invested.

The person running your local Bio-One isn’t just in the business—they’re part of your neighborhood. They know the area, understand what you’re going through, and care about making a real difference. Trained and certified, they lead a team that shows up 24/7 with compassion, discretion, and respect.

When you call, you’re not getting a stranger. You’re getting a neighbor who’s ready to help.

Ryan Lowe

Ryan Lowe is the owner of Bio-One, located in Delaware. Ryan grew up in Newark and attended the University of Delaware, where he earned his Bachelor's Degree, as well as his MBA. Ryan has a passion for serving his community and helping others, and has been a Professor at the University of Delaware for more than a decade, where he teaches his students how to help others as well. His years of experience and expertise are exhibited when he and his team help in restoring their client's properties to their original condition in a professional and compassionate manner. Ryan and his wife, Kristi, have two daughters and are active members in their church.

Stronger Communities Start with Compassion

More than cleanup—it’s about community. We go beyond cleanup to support real people in real need. We’re not just here to clean. We’re here to care.

Bio-One works closely with first responders, local agencies, and community groups to help those facing crisis, loss, or trauma.

We support local efforts to promote safety and healing.
We show up when people need real help.
We give back however we can—because this work is personal.

No matter how we grow, our mission stays the same: Always put people first, help with heart, and do the right thing.

Find your nearest Bio-One office

303-865-4262

Schedule a Service

What our clients say

Ellen Greenberg Sheridan, Delaware, 05/2024

Had an amazing experience with Ryan, Bio-one. He literally came to the rescue to my son’s off campus house in Newark to clean a sewage backup in their basement. He came after doing another job in southern Delaware when he probably should have been home having dinner with his family. He not only had the physical health of my son and roommates in mind, but the mental health of worried parents many miles away. Ty Ryan!

Claudia Beckmann, Delaware, 04/2024

My husband was pretty immobile the last year of his life and spent most of his time in a recliner. The month before he died he was incontinent of both urine and feces. After he died his recliner reeked of urine. We tried everything we could think of to get rid of the odor but it was still there. I was afraid we were going to have to dispose of the chair. Finally I called Bio-one Delaware and spoke with Matt Lowe, the owner. He told me he would be glad to take a look at the chair but also warned me that urine was very difficult to get rid of. I decided to have him see what he could do and he came out and sprayed the chair with a pet and environment friendly substance. He covered the chair in plastic so the chemicals could be absorbed and came out the next day. I cannot detect the odor of urine any more! Matt was very professional--he came when he said he would be there and he followed up with me. His prices are very reasonable and I would not hesitate using him again and will tell my friends! Thank you so much!

Jennaayy Colletti, Delaware, 04/2024

God sent us two angels of the worst day of my family’s life. Ryan and Kristi came to us after a very tragic murder/suicide occurred in my parents home. They did a fabulous job cleaning all areas affected. The energy of the house shifted to peace despise such a horrible incident. They absolutely went above and beyond for my mother in her time of need. We can’t say enough nice things about them. They really took the time and spent long hours to make sure everything was spotless. We can’t thank them enough. ❤️

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Experts Who Care and Know What They’re Doing

Trained, certified, and ready for anything.

Every Bio-One technician is highly trained in biohazard cleanup. But it’s not just about skills—it’s about heart. We show up with:

Industry certifications
Real-world experience
A calm, compassionate approach

We know how to handle challenging situations safely, quickly, and with total care for the people involved.

Our Promise to You

We treat every job—and every person—with care and respect. These aren’t just words—they’re how we work, every time.

At Bio-One, we don’t just clean. We listen. We show up with kindness, work with integrity, and protect your privacy every step of the way.

We’re discreet and respectful.
We follow through on what we say.
We treat your space like it’s our own.

No judgment. No shortcuts. Just honest help when you need it most.

Certifications and Achievements

How We Started and Why It Matters

Helping first. Always.

Over 20 years ago, Bio-One was founded with one clear goal: to help people through the most challenging times of their lives.

Our founder believed no one should face trauma or tragedy alone. That’s why we lead with care, not profit. From a small start to serving families, businesses, and even government agencies nationwide—we’ve stayed true to our mission:

Help first. Business second. Make a real difference.

Our Vision

We’re here to serve—with experience, compassion, and respect. Our mission is simple: help people in their most challenging moments by providing expert biohazard cleanup.

At Bio-One, we’re here to help—today and tomorrow. Our vision is to lead the industry with:

Compassion for every client
Expertise in every job
Respect in every interaction

We’re shaping the future of biohazard cleanup through compassion and care—because how we help matters just as much as what we do.

WORK WITH US

Ready When You Need Us

Compassionate help is just a call away.

Need expert cleanup? We’re here 24/7—no judgment, no delays.

Whether you're facing a crisis or just have questions, our team is ready to help with care, skill, and respect.

Call us anytime at 302-893-3595

We’re just one call away from helping you feel in control again. We’ll be there when it matters most.

Schedule a Service

Frequently asked questions

What types of situations does Bio-One handle?

We specialize in cleaning the unimaginable—crime scenes, hoarding, biohazards, unattended deaths, and more. Our services are designed to bring comfort and peace of mind during life’s toughest moments.

Is Bio-One available in my area?

Yes. Bio-One is locally owned and operated across the country. That means you’ll always work with someone who understands your community and shows up with compassion, not judgment.

How quickly can Bio-One respond?

We’re available 24/7 and pride ourselves on fast response. When you call, we act quickly—because we know timing matters in a crisis.

What does the cleanup process look like?

It starts with your call. Then we arrive, assess the situation, explain next steps, clean and disinfect thoroughly, and walk through everything with you before we leave. Our goal is to restore both your space and your peace of mind.

Is your cleanup team trained and certified?

Absolutely. Every Bio-One technician is certified, highly trained in biohazard cleanup, and brings real-world experience with a calm, respectful approach.

Will Bio-One help with my insurance claim?

Yes. We work directly with insurance providers to ease the process and reduce stress for you.

What makes Bio-One different from other cleanup companies?

We lead with compassion. Our motto is “Help First, Business Second,” and that shows in every interaction. We treat every space—and every person—with care, respect, and zero judgment.

How does Bio-One protect my privacy during cleanup?

We’re discreet and professional at every step. We arrive unmarked (when requested), follow strict confidentiality protocols, and treat your space like it’s our own.

Who can call Bio-One for help?

Anyone. We serve homeowners, business owners, law enforcement, public agencies, and more. If you’re facing a tough situation, we’re here to help.

What does Bio-One mean by “more than a cleanup crew”?

It means we don’t just clean—we care. We support local communities, work with first responders, and show up with heart, not just hazmat suits.