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We’re Here When You Need Us Most

Bio-One is the leading name in crime, hoarding scene cleanup, and biohazard decontamination services. When life gets overwhelming, Bio-One is ready to help.

Our mission has been simple for over twenty years: help first, business second—and that’s exactly how we show up.

Questions? Need a Bio-One service? How can we help?

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    Fentanyl Remediation
    IICRC Badge
    OPEN 24/7

    No matter when you call, we’re ready.

    Our local Bio-One technicians respond quickly, walk you through every step, and handle the cleanup with care and respect.

    We follow a detailed plan to clean, organize, and safely remove any biohazards—restoring your space and giving you peace of mind.

    Need help now? Call us 24/7: 302-893-3595

    Schedule a Free Consultation

    Your Support Matters to Us

    If we’ve helped you through a tough time, we’d be honored to hear about it.

    Sharing your experience helps others know they’re not alone—and that trusted help is out there.

    Leave us a review on our Google Business Profile.

    Thanks for Trusting Us

    If you'd like to share your experience, we’d love to hear it.

    What our clients say

    decontamination and biohazard cleaning services reviews
    Ellen Greenberg Sheridan, Delaware, 05/2024
    Had an amazing experience with Ryan, Bio-one. He literally came to the rescue to my son’s off campus house in Newark to clean a sewage backup in their basement. He came after doing another job in southern Delaware when he probably should have been home having dinner with his family. He not only had the physical health of my son and roommates in mind, but the mental health of worried parents many miles away. Ty Ryan!
    decontamination and biohazard cleaning services reviews
    Claudia Beckmann, Delaware, 04/2024
    My husband was pretty immobile the last year of his life and spent most of his time in a recliner. The month before he died he was incontinent of both urine and feces. After he died his recliner reeked of urine. We tried everything we could think of to get rid of the odor but it was still there. I was afraid we were going to have to dispose of the chair. Finally I called Bio-one Delaware and spoke with Matt Lowe, the owner. He told me he would be glad to take a look at the chair but also warned me that urine was very difficult to get rid of. I decided to have him see what he could do and he came out and sprayed the chair with a pet and environment friendly substance. He covered the chair in plastic so the chemicals could be absorbed and came out the next day. I cannot detect the odor of urine any more! Matt was very professional--he came when he said he would be there and he followed up with me. His prices are very reasonable and I would not hesitate using him again and will tell my friends! Thank you so much!
    decontamination and biohazard cleaning services reviews
    Jennaayy Colletti, Delaware, 04/2024
    God sent us two angels of the worst day of my family’s life. Ryan and Kristi came to us after a very tragic murder/suicide occurred in my parents home. They did a fabulous job cleaning all areas affected. The energy of the house shifted to peace despise such a horrible incident. They absolutely went above and beyond for my mother in her time of need. We can’t say enough nice things about them. They really took the time and spent long hours to make sure everything was spotless. We can’t thank them enough. ❤️

    Frequently asked questions

    Why should I contact Bio-One?
    If you're facing a situation involving biohazards, hoarding, or trauma-related cleaning, Bio-One is here to help. We specialize in sensitive, urgent cleanup needs and respond with compassion, discretion, and professionalism.
    What types of situations can I contact Bio-One about?
    You can contact us for help with unattended deaths, hoarding cleanup, suicide or homicide cleanup, sewage backups, rodent droppings, mold, and more. If you’re unsure, just reach out—we’ll guide you.
    How quickly will someone respond after I contact you?
    We aim to respond within minutes, 24/7. Your message is sent directly to a local owner or dispatcher, so you’re not left waiting in a queue.
    Do I have to be the homeowner or property owner to contact you?
    No. We regularly work with family members, landlords, property managers, social workers, law enforcement, and others who are involved in helping someone in need.
    What if I’m just not sure what kind of help I need?
    That’s okay. You don’t need all the answers—we’re here to listen and help you figure out the next steps. Just tell us what’s going on.
    Is my information kept private when I contact you?
    Yes. Every call, form, and message is kept completely confidential. We understand the sensitive nature of the situations we deal with.
    Can I reach you outside of normal business hours?
    Absolutely. Bio-One is available 24 hours a day, 7 days a week—including holidays. Emergencies don’t wait, and neither do we.
    What happens after I submit the contact form?
    A local Bio-One owner or certified specialist will contact you shortly—often by phone—to learn more and help schedule an in-person assessment or service visit.
    Do I have to pay just to talk to someone or get information?
    No. Contacting us is always free. We’ll give you honest answers, explain what we do, and help you decide what’s best for your situation—no pressure.
    How do I know I can trust Bio-One with something this important?
    We’ve helped thousands of families and property owners through some of life’s hardest moments. Our mission is simple: Help First, Business Second. We're here when you need us.