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We’re Here When You Need Us Most

Bio-One is the leading name in crime, hoarding scene cleanup, and biohazard decontamination services. When life gets overwhelming, Bio-One is ready to help.

Our mission has been simple for over twenty years: help first, business second—and that’s exactly how we show up.

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Questions? Need a Bio-One service? How can we help?

    OPEN 24/7

    No matter when you call, we’re ready

    Our local Bio-One technicians respond quickly, walk you through every step, and handle the cleanup with care and respect.

    We follow a detailed plan to clean, organize, and safely remove any biohazards—restoring your space and giving you peace of mind.

    Need help now? Call us 24/7: 317-435-1611

    Schedule a Free Consultation

    Your Support Matters to Us

    If we’ve helped you through a tough time, we’d be honored to hear about it.

    Sharing your experience helps others know they’re not alone—and that trusted help is out there.

    Leave us a review on our Google Business Profile.

    Thanks for Trusting Us

    If you'd like to share your experience, we’d love to hear it.

    What our clients say

    decontamination and biohazard cleaning services reviews
    Drake Byrn, Madison County, 03/2024
    I called Bio-One for help with raccoon feces in my attic as the exterminators wouldn’t remove it. They came out and gave us a free estimate and started the work right away after we agreed on a price. The young men were precise and worked quickly. The work completed by Richard and his team is without a doubt magnificent.
    decontamination and biohazard cleaning services reviews
    Logan Sutt, Madison County, 03/2024
    We had a pipe burst in our crawlspace and the plumber said we needed a bio company to chemically treat and remove the sewage. I called Bio-One NW Indianapolis late at night as the website says 24 hours. They not only cleaned the sewage up they put down plastic so we could have a cleaner entry! Easily the best company I called, money well spent.
    decontamination and biohazard cleaning services reviews
    Justin T, Madison County, 03/2024
    We had a tragedy in the family I called Bio-One they came out within an hour and got started. They guided me every step of the way. The empathy and compassion l the team provides to clients is unheard of in my experience. Thank you so much Richard and team.

    Frequently asked questions

    Why should I contact Bio-One?
    If you're facing a situation involving biohazards, hoarding, or trauma-related cleaning, Bio-One is here to help. We specialize in sensitive, urgent cleanup needs and respond with compassion, discretion, and professionalism.
    What types of situations can I contact Bio-One about?
    You can contact us for help with unattended deaths, hoarding cleanup, suicide or homicide cleanup, sewage backups, rodent droppings, mold, and more. If you’re unsure, just reach out—we’ll guide you.
    How quickly will someone respond after I contact you?
    We aim to respond within minutes, 24/7. Your message is sent directly to a local owner or dispatcher, so you’re not left waiting in a queue.
    Do I have to be the homeowner or property owner to contact you?
    No. We regularly work with family members, landlords, property managers, social workers, law enforcement, and others who are involved in helping someone in need.
    What if I’m just not sure what kind of help I need?
    That’s okay. You don’t need all the answers—we’re here to listen and help you figure out the next steps. Just tell us what’s going on.
    Is my information kept private when I contact you?
    Yes. Every call, form, and message is kept completely confidential. We understand the sensitive nature of the situations we deal with.
    Can I reach you outside of normal business hours?
    Absolutely. Bio-One is available 24 hours a day, 7 days a week—including holidays. Emergencies don’t wait, and neither do we.
    What happens after I submit the contact form?
    A local Bio-One owner or certified specialist will contact you shortly—often by phone—to learn more and help schedule an in-person assessment or service visit.
    Do I have to pay just to talk to someone or get information?
    No. Contacting us is always free. We’ll give you honest answers, explain what we do, and help you decide what’s best for your situation—no pressure.
    How do I know I can trust Bio-One with something this important?
    We’ve helped thousands of families and property owners through some of life’s hardest moments. Our mission is simple: Help First, Business Second. We're here when you need us.
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