Help First, Business Second

Winston-Salem Biohazard Cleanup Service

When a biohazard happens, it can feel overwhelming. This work isn't just cleanup—it’s support for people in crisis. That’s what Bio-One of Winston-Salem is here to provide: expert biohazard cleaning services with real heart behind it.

When someone calls us, they’re often unsure of what to do next. We guide people through what can feel like chaos and bring calm to the situation. Our local team is available 24/7 to help you take the next step forward.

We're trained to handle a wide range of hazardous cleanups with care, safety, and compassion. We offer crime scene, suicide, and unattended death cleanup for many clients. That includes homes, businesses, vehicles—anywhere that needs to be made safe again. We respond quickly and work thoroughly so you can focus on what matters most.

  • Available 24/7 for urgent calls—day, night, weekends, or holidays.
  • Certified and experienced in bloodborne pathogen and hazmat cleanup.
  • Handle everything from sewage backups to unattended deaths and chemical exposures.
  • Work directly with insurance to make things easier on families.
  • You don’t have to face this alone—we’ll walk through it with you.

We make sure the space is cleaned thoroughly, documented properly, and safe to enter again. Every job gets our full attention, from proper safety protocols to the compassion we show every person we help.

Emergency response hotline

Call now to reach our Winston-Salem crime scene and biohazard cleaning team.

Call me directly: Nadine Black and Anthony Coleman
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Elizabeth Glenn

Friend’s family used BioOne to clean up after we found her deceased. They returned when it was time to clean out remaining belongings. I came to collect a few sentimental items set ...

Tonya Clark

These people are angels. My aunt is a hoarder and they came in and made her house a home again. Thank you guys for all that you have done. You have rescued my family and myself from ang...

Christina Taylor

I needed to have my dad’s house cleaned before he returned home from a major surgery. The house had endured decades of neglect through renters and smokers inside the home. Bio-One wa...

Sam Howard (PsyMar)

Cleaned my basement, which I couldn't stand the smell anymore because something the cat dragged in had died. It now looks fantastic, couldn't be cleaner. A+ job, this is my second tim...

Karen Johnson Tucker

Personable and friendly techs. Very accommodating and mostly followed directions. I had some issues with stored items but the lead guy came back and did an outstanding job of rearrangin...

Trusted By
Decontect Fentanyl Response Certification - Nadine Black

You called the right team for the job

We start and end every job with compassion and caring. Our clients trust us because we bring calm to uncalm situations and do the hard work with heart.

  • We show up fast and ready to help: We're available 24/7 and usually respond within a couple hours—sometimes even faster.
  • We walk you through it step by step: Our lead tech will talk through everything on-site and make sure you're comfortable before we start.
  • We know what we’re doing: Our crew is trained, experienced, and serious about doing the job right—from safety protocols to documentation.
  • We work with respect and discretion: We don’t use marked vehicles or draw attention to your situation.
  • We manage the insurance process for you We’ll help with claims, pictures, documentation—whatever makes it easier on the client.
  • We lead with compassion Always. This isn’t just cleanup—it’s emotional support. That’s how we see it.

When the unexpected happens, we’re just trying to give people some sense of peace. That’s what makes us different.

 

You’re not alone. We’re here day or night.

What It’s Like to Work With Bio-One

Every biohazard and crime scene cleanup starts with compassion—and ends when the family says it’s done. That’s how we operate. We’re not just getting in and out—we’re there to guide and support people all the way through.

Here’s what to expect:

 

Our first conversation is just about listening—learning what’s going on, what they’re dealing with. Whether we visit the space or review photos, we talk through everything in plain terms, no pressure, and offer an honest estimate.

We treat the space with respect and adjust to what the client wants. That could mean recovering keepsakes, removing hazardous items, or just quietly getting it all out so they can breathe again. Every step is handled with safety and discretion.

We go beyond surface-level. That includes deep cleaning, odor removal, and making sure it’s livable, functional, and feels like a home again. We don’t cut corners—especially in the hidden ones.

We’ve had a lot of success helping families with insurance claims. From documentation to adjuster coordination, we handle it from start to finish so they don’t have to stress about the paperwork.

Some families we still talk to, months later. Whether you need resources or just a check-in, we let people know—we’re still here.

We’re here for the full journey—not just the cleanup.

We explain everything clearly—no surprises, no confusion.

 

We respond 24/7.
Request a service now.

Begin your cleanup journey.

    WE'RE READY 24/7

    Work with us

    Three steps. Full compassion.
    1

    Always open. Always ready.

    When a customer calls us, they can expect to be greeted with compassion, discretion, and a caring heart.
    2

    In Person, With Heart.

    We meet you where you are—literally and emotionally. We’ll come out, walk the space with you, and make a plan that’s just right for your situation.
    3

    You’re Not Alone.

    We support families throughout the entire process—and beyond. We even work directly with your insurance company to make the process easier.

    What makes Bio-One Suicide and Homicide Cleanup Service in Winston-Salem the Best Choice?

    Expert services

    With trained technicians and state-of-the-art tools, we can handle any biohazard job, whether residential, commercial, or industrial. We have the training and experience you are looking for.

    Discreet & safe

    Discretion and confidentiality are important to our clients. Our teams will arrive and complete the job thoroughly and safely.

    Blood Spill Cleanup Icon

    Compassion & competence

    Our motto is "Help first, business second." Our team leads with compassion and serves our clients with respect and professionalism.

    Available 24/7

    Bio-One is here for you whenever you need us. You will receive 24/7 access to a local company with nationwide expertise.

    Trusted response team

    A quick response team can significantly impact biohazard situations. Our teams respond urgently and are ready to help.

    Insurance assistance

    Working with your insurance company can be overwhelming. Bio-One can open the claim and work with the adjusters directly.

    Call Us 24/7
    Compassion. Experience. Respect.

    We’re Here—Day or Night, No Matter What

    Trying to clean up a biohazard on your own can put your health at risk. Most people don’t realize how dangerous it can be—especially without the right safety protocols and equipment. Blood, bodily fluids, and chemical residues carry risks that go far beyond what household cleaners can fix. We have the proper training to handle the crime scene, biohazard or hoarding cleanup process.

    • We’re trained and certified to handle serious biohazards—this is all we do.
    • Without protection, even touching the wrong surface can expose you to something dangerous.
    • There’s a right way to clean, and we make sure it’s done by the book.

    We’re available 24/7 because people don’t plan for this. From OSHA compliance to careful documentation, we clean and disinfect the right way—safely and thoroughly.

    • We arrive discreetly and work quickly to resolve the issue.
    • We protect and set aside valuables when possible—sentimental items matter.
    • When we leave, your space is clean, documented, and safe to return to.

    Every call is different, and we treat it that way—whether it's a home, a car, or a business, we handle it with care and respect.

    Every call is different, and we treat it that way—whether it's a home, a car, or a business, we handle it with care and respect.

     

    Proud to Serve Our Neighbors Across the Piedmont Triad

    We live here, we care, and we’re proud to serve our neighbors.

    We’re not just based in Winston-Salem—we’re deeply connected to this community and the surrounding areas. We service the Winston-Salem and Piedmont Triad area here in North Carolina, and that means showing up for people during tough moments, no matter where they are.

    From private homes to local government and public agencies, we bring discretion, compassion, and professionalism to every job. Whether you’re in a small town or a busy city, we’re here to provide calm, clarity, and real help when things feel overwhelming.

    • Cleanup of hazardous materials including blood, bodily fluids, and contamination.
    • Certified in handling complex and high-risk environments.
    • Thoughtful service from people who genuinely care and listen.
    • Quick, local response when every minute counts.
    • We treat your space with dignity—because it’s more than just walls and floors.

    Our team continues to grow throughout our region together, and we’re honored to be part of the solution when people need a hand.

    You’ll also find us working with trusted organizations like:

    • Forsyth County Government
    • NC Department of Public Safety
    • Winston-Salem and Greensboro Police & Fire Departments
    • High Point Police & Fire
    • Winston-Salem State University

    we proudly serve:

    • Winston-Salem
    • Greensboro
    • High Point
    • Burlington
    • Salisbury
    Find your nearest Bio-One office

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    What our clients say

    decontamination and biohazard cleaning services reviews
    Alanna Greer, Winston-Salem, 12/2024
    If I could give this company more than 5 stars I would. I hired this team to clean out my grandmothers down stairs that has been victim to animal feces and hoarding for the past 20 years. They were extraordinarily kind, professional, and discreet. I scheduled with Nadine who was so helpful with planning. I made a mistake in my scheduling and she immediately jumped on helping me fix it and making this whole process easy. Chris and his team were so patient during the whole process. All three members of this team went through great lengths to make sure my grandmother was comfortable with what was being cleaned and taken out. This company absolutely fits individual needs and truly listens to your unique situation. I couldn’t have asked for better help. They turned a nightmare situation into a miracle. Thank you all!
    decontamination and biohazard cleaning services reviews
    Christina Taylor, Winston-Salem, 11/2024
    I needed to have my dad’s house cleaned before he returned home from a major surgery. The house had endured decades of neglect through renters and smokers inside the home. Bio-One was incredible to work with. They were prompt and communication, quick to give a quote, and flexible with different cleaning options. Christopher led the team that came out to clean. Each person I spoke with was kind and professional. I’m amazed at how well everything was cleaned; It looks like an entirely new space! The price was very reasonable considering the amount of work they put in. I also live out of town, but Bio One made it so easy to lineup the details. I highly recommend them to anyone Needing a thorough clean and/or disposal of hoarded items.
    decontamination and biohazard cleaning services reviews
    Todd F, Winston-Salem, 09/2024
    Excellent company to work with. Perfect communication and follow through from the first phone call. Fast, fair estimate and amazing turnaround on the service. They really stepped up in a big way with a time sensitive need. Could not recommend more highly!

    Frequently asked questions

    What is biohazard cleanup?
    Biohazard cleanup means removing and disinfecting anything contaminated with blood, bodily fluids, chemicals, or other dangerous materials. We make sure the space is cleaned the right way—so it’s safe to use again.
    What kinds of situations require this service?
    We’re called in after suicides, unattended deaths, accidents, hoarding, drug residue, sewage backups, and even homeless encampments. If something feels unsafe, overwhelming, or hazardous, that’s when we step in.
    Is it dangerous to clean up a biohazard myself?
    Yes. Most people don’t realize how dangerous it can be—especially without the right safety protocols and equipment. It’s easy to be exposed to harmful bacteria or bloodborne pathogens. That’s why we follow OSHA regulations and wear proper protective gear.
    How fast can you get here?
    We’re available 24/7 and usually respond within a couple hours—sometimes even faster. Nights, weekends, and holidays—we answer the phone when others won’t.
    Will your crew be discreet?
    Yes. We don’t use marked vehicles or draw attention to your situation. Our team works quietly and respectfully—we treat every person and space with care.
    How do I know the area is fully cleaned?
    We follow strict cleaning standards and double-check every surface. We disinfect, remove dangerous items, and document everything. When we leave, your space is clean, documented, and safe to return to.
    Do you remove items that can’t be cleaned?
    Yes. If something is too contaminated to save—like carpeting or furniture—we’ll let you know and remove it properly. We protect and set aside valuables when possible—sentimental items matter.
    Can you help with the insurance claim?
    Absolutely. We’ll help with claims, pictures, documentation—whatever makes it easier on the client. Many cleanups are covered under homeowners’ insurance, and we’ll walk you through it step by step.
    What if I’m not sure where to start?
    That’s okay. Most people aren’t. Our first conversation is just about listening—learning what’s going on, what they’re dealing with. From there, we’ll explain your options and help you decide what’s best.
    What makes Bio-One of Winston-Salem different?
    We start and end every job with compassion. This isn’t just cleanup—it’s emotional support. Our team is local, experienced, and focused on helping people move forward.
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